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Mother’s Malaria Can Affect Memory In Offspring

Malaria infection during pregnancy may result in learning and memory related problems in offspring, suggests new research.

This is because maternal malaria infection alters the formation of blood vessels in the brains of exposed offspring.

The exposed fetus has smaller blood vessels in its brain than the control fetus, the findings showed.

These results “highlight a novel mechanism by which malaria in pregnancy may alter the neurocognitive development of millions of children prior to birth”, the researchers said.

In this study, Kevin Kain, from the University of Toronto, Canada, and colleagues specifically examined neurocognitive function in mice of normal birth weight that had been exposed to — but not themselves infected with — malaria in the uterus.

The researchers found that young mice that had been exposed to malaria in pregnancy have impaired learning and memory and show depressive-like behaviour that persists to adulthood.

These neurocognitive impairments are associated with decreased tissue levels of major neurotransmitters (serotonin, dopamine, and norepinephrine) in specific regions of the brain.

By imaging blood vessels in the uterus, the researchers also saw changes in neurovascular development in the brain of malaria-exposed mouse fetuses.

The findings appeared in the journal PLOS Pathogens.

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Posted by on September 28, 2015. Filed under HEALTH. You can follow any responses to this entry through the RSS 2.0. Both comments and pings are currently closed.

4 Responses to Mother’s Malaria Can Affect Memory In Offspring

  1. pillar

    September 28, 2015 at 9:53 am

    some useless UPND fools will balme PF for this,wait and see

    • New Educated Zambia©❤√

      September 28, 2015 at 10:43 pm

      it must have affected many pf cadres’ mothers because most of them seem to have a short memory span as they forget the suffering they go through under pf when they decide to vote pf.

  2. tutu

    September 29, 2015 at 4:24 am

    m 100% sure chikala chakwe nez is a victim of this!

    • New Educated Zambia©❤√

      September 29, 2015 at 7:49 am

      Kiki silly insignificant pf cadre. Atleast you have now being tamed. You and that other nasty piece of work chief of grief. Silly kids