Women with bigger br*asts DO have higher risk of breast cancer, finds genetic study
Women with a large bust may be more likely to develop breast cancer, according to scientists.
A study of 16,000 women found genetic mutations associated with breast size were also linked to the disease.
Researchers say some of these are involved in regulating the female sex hormone oestrogen, which can trigger the growth of both breasts and tumours.
While research has linked breast density – the amount of non-fat tissue – to an increased risk of cancer, there has been little evidence of a link with breast size before.
Participants in the study, carried out by a US company, were asked to give their bra size on a 10-point scale from smaller than AAA to larger than DDD.
The genetic code of the women – all of European origin – was read by scientists who looked through millions of tiny mutations in their DNA, called single-nucleotide polymorphisms. Out of seven that were strongly linked to breast size, three were also associated with breast cancer.
Breast cancer is the most common form of the disease in Britain, with 50,000 new cases a year and one in eight women affected during their lifetime.
Dr Nicholas Eriksson of the California-based genetics firm 23andMe said it was the first substantial link between breast size and cancer, but added much more research was needed before it could be considered concrete.
He said: ‘Our results identify genetic variants that have an effect on both breast cancer and natural variation in breast size.
‘While the precise relationships between breast size, density, obesity and breast cancer remain difficult to untangle, understanding the biology . . . may aid in the development of novel screening tools.’
He said one of the three mutations regulates the activity of the oestrogen receptor gene that plays a vital role in breast growth and in the majority of breast cancer cases.
Another is located in a region of a woman’s genome that often shows abnormalities in those with certain types of breast cancer.
The link was seen regardless of the women’s age, pregnancy and breastfeeding history and genetic ancestry, according to the study published in the journal BMC Medical Genetics.
Little is known about the biology of breast size, which scientists believe is only half hereditary, but high oestrogen levels are known to be a risk factor for breast cancer.
There are many different forms of breast cancer, which scientists believe could be treated as ten different illnesses. Weight, alcohol consumption and a strong family history are all risk factors.
A 2006 study by the Harvard School of Public Health on 90,000 pre-menopausal subjects found larger breast size in slim young women gave them a higher risk of breast cancer in later life.
Those with a body mass index of 25 or less and a bra size of D or larger had a significantly higher risk of breast cancer than those of the same weight with a cup size A or smaller, they found.
However, the study’s lead author, Karin Michels, said the findings did not mean those with small breasts could assume they were safe and urged all women to go for breast cancer screening.
DailymailUK
If You Have Big Br*asts, It Is Important You Read This… added by on
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AM I THE FIRST ONE TO COMMENT?
Men love a woman with big boobs end of story.
stopped to admire big boobs, i like mine the way they are.
@Candy Babes, do they look lyk neck ties or sumthng? Lol mwandi i luv yoz babe
@candy babes i lyk yo boobz too…
Ni boza
Deng!! whatever was in the story? I couldnt get past the big boobs in the picture. So im going back to looking at them!!
they are nice and some of these facts are to create money others when women decides to go for operations.
pliz tel ms Siliya to go for checkup,she might be one of the victims
owez learn 2 undastand b4 u tok
Ala nalitemwa ukonka amabele mwebantu. Sex nshaitemwa nangu panono. Kano ibele especially ilya kwa Dora uuuuuhhhhhhmmmmm ni ziiii! Ama congolese mu neighbourhood mwandi nalabocha.
Mmm imwe ni boza yokanga iyi.Breast cancer is inherited in most cases. Tuzungu are prone to BC and have small bazumas if not implants!Elo situnyomsa.My family have large bossoms none of them av it.
Big boobs for lyf,luv them wen lickin them.
If that’s true then i am screwed!!!
Awe ayayena ya kulisha mwe.
My grandmama is 90 and has big boobs when is she gona have breast cancer?
Appealing to the Girls who buy medicine for breast enlargement to stop? because maybe the some medicine are carrying cancer after some years
Its not true that all men like big boobs,sizeable boobs are better.utwafota utwakopoka nato teto,tulaleta umuselu mwukwai.
my girlfriend hs these amazingly nyc boobs but nt so big….& each tym she squeezes them on my chest so tyt!!….i love her 2 da max…so u scientists gotta make some otha research!!
Big br—–st are gud 4 lif evry 1 likes it, tou too likes utusungu twabufi sana.They want to make money over it.